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CASP10 Polyclonal Antibody

CASP10 Polyclonal Antibody

Item no.	E-AB-13820-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Signaling Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Immunohistochemistry ELISA Cardiovascular Research Ischemia & Reperfusion Injury Enzymes Fatty Acid Synthesis Primary Antibodies By Organ Skin Cancer Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Lymphatic System Cancer Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALPS2, Apoptotic protease Mch-4, CASP 10, CASP-10, CASP10, CASPA, Caspase 10 apoptosis related cysteine peptidase, Caspase-10 subunit p12, FADD like ICE2, Fas associated death domain protein, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE 2, FLICE2, ICE like apoptotic protease 4, ICE-like apoptotic protease 4, Interleukin 1B converting enzyme 2, MCH 4
Similar products	CASP10, ALPS2, FLICE2, ICE-like apoptotic protease 4, CASPA, CASP 10, Caspase 10 apoptosis related cysteine peptidase, FLICE 2, MCH 4, Apoptotic protease Mch-4, CASP-10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, Caspase-10 subunit p12, FADD like ICE2, Fas associated death domain protein, ICE like apoptotic protease 4, Interleukin 1B converting enzyme 2
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CASP10
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	Cancer, Cell Biology, Metabolism
Background	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Concentration	0.2 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	IHC 1:25-1:100
Santa Cruz #	sc-22184, sc-6184, sc-6186, sc-6185, sc-7955
Abbreviation	CASP10
Clonality	Polyclonal
Immunogen	Recombinant protein of human CASP10
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.