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MCM3 Polyclonal Antibody

MCM3 Polyclonal Antibody

Item no.	E-AB-33487-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Regulation of Appetite Aging & Neurological Disorders Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Proliferation Primary Antibodies By Organ Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Applications	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, DNA polymerase alpha holoenzyme associated protein P1, DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, DNA replication licensing factor mcm3, HCC 5, HCC5, hRlf beta subunit, Human cervical cancer proto oncogene 5, MCM 3, mcm3, MCM3 minichromosome maintenance deficient 3, MCM3, MGC1157, Minichromosome maintenance complex component 3, Minichromosome maintenance deficient 3, Minichromosome maintenance protein 3, P1 h, P1 MCM3, P1 Protein, P1-MCM3, P1.h, p102, P102 protein, Replication licensing factor beta subunit, RLF beta subunit, RLF subunit beta, RLFB
Similar products	MCM3, p102, mcm3, HCC5, MGC1157, P1-MCM3, P1.h, RLFB, DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, MCM3 minichromosome maintenance deficient 3, hRlf beta subunit, RLF subunit beta, Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, HCC 5, Human cervical cancer proto oncogene 5, MCM 3, Minichromosome maintenance complex component 3, P1 h, P1 MCM3, Replication licensing factor beta subunit, RLF beta subunit, DNA polymerase alpha holoenzyme associated protein P1, DNA replication licensing factor mcm3, Minichromosome maintenance deficient 3, Minichromosome maintenance protein 3, P1 Protein, P102 protein
Available
Storage Conditions	Store at -20C. Avoid freeze / thaw cycles.
Calculated Molecular Weight	89kDa
Observed Molecular Weight	89kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Background	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Santa Cruz #	sc-9849, sc-9850
Immunogen	Synthesized peptide derived from the Internal region of human MCM3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 120 uL

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Delivery expected until 9/11/2025

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