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(KO Validated) BCL10 Polyclonal Antibody

(KO Validated) BCL10 Polyclonal Antibody

Item no.	E-AB-60188-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 200 uL 60 uL
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Hematology Myeloma Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies By Organ Skin Cancer Heart & Blood Cancer Lymphatic System Cancer
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BCL10, CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
Similar products	Bcl-10, BCL10, Bcl10, CARMEN, CIPER, CLAP, c-E10, mE10, CARD containing molecule enhancing NF-kB, CARD-containing apoptotic signaling protein, CARD-containing proapoptotic protein, Bcl 10, B cell CLL/lymphoma 10, B cell lymphoma/leukemia10, B-cell leukemia/lymphoma 10, c E10, C81403, CARD containing apoptotic signaling protein, CARD containing molecule enhancing NF kappa B, CARD containing molecule enhancing NF kB, CARD containing molecule enhancing NFkB, CARD containing proapoptotic protein, CARD like apoptotic protein, Caspase recruiting domain containing protein, cCARMEN, cE 10, cE10, CED 3/ICH 1 prodomain homologous E10 like regulator, CED3/ICH1 prodomain homologous E10 like regulator, Cellular E10, Cellular homolog of vCARMEN, hCLAP, Mammalian CARD containing adapter molecule E10, mE 10, R-RCD1, AI132454
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	BCL10
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	26kDa
Observed Molecular Weight	33kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Metabolism, Signal Transduction
Background	This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000
Abbreviation	BCL10
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human BCL10 (NP_003912.1).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.