PSMB2 Polyclonal Antibody

PSMB2

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

23kDa

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200

Polyclonal

Polyclonal Antibodies