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P53 Polyclonal Antibody

P53 Polyclonal Antibody

Item no.	E-AB-32466-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Western Blot ELISA Primary Antibodies Astrocytoma By Organ Lung Cancer Bladder Cancer Breast Cancer
Type	Antibody Polyclonal
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Antigen NY-CO-13, BCC7, Cellular tumor antigen p53, FLJ92943, LFS1, Mutant tumor protein 53, p53, p53 tumor suppressor, P53, Phosphoprotein p53, Tp53, Transformation related protein 53, TRP53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53
Similar products	p53, P53, TRP53, Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, Tp53, FLJ92943, LFS1, p53 tumor suppressor, BCC7, Transformation related protein 53, Tumor protein p53, Mutant tumor protein 53, Tumor protein 53
Available
Storage Conditions	Store at -20C. Avoid freeze / thaw cycles.
Calculated Molecular Weight	44kDa
Observed Molecular Weight	53kDa
Research Areas	Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Background	The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000, ELISA 1:20000
Immunogen	Synthesized peptide derived from human p53 around the non-acetylation site of K381

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 60 uL

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Delivery expected until 7/10/2025

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