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KCNQ4 Polyclonal Antibody

KCNQ4 Polyclonal Antibody

Item no.	E-AB-16544-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Antibodies Immunohistochemistry Western Blot ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14700
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DFNA 2, DFNA2, KCNQ 4, Kcnq4, KCNQ4, KQT like 4, KQT-like 4, KV7.4, Potassium channel KQT like 4, Potassium channel subunit alpha KvLQT4, Potassium voltage gated channel KQT like protein 4, Potassium voltage gated channel KQT like subfamily member 4, Potassium voltage gated channel subfamily KQT member 4, Potassium voltage-gated channel subfamily KQT member 4, Voltage gated potassium channel subunit Kv7.4, Voltage-gated potassium channel subunit Kv7.4
Similar products	KCNQ4, DFNA2, KV7.4, Kcnq4, DFNA 2, Potassium voltage-gated channel subfamily KQT member 4, KQT-like 4, Potassium channel subunit alpha KvLQT4, Voltage-gated potassium channel subunit Kv7.4, KCNQ 4, KQT like 4, Potassium channel KQT like 4, Potassium voltage gated channel KQT like protein 4, Potassium voltage gated channel KQT like subfamily member 4, Potassium voltage gated channel subfamily KQT member 4, Voltage gated potassium channel subunit Kv7.4
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	KCNQ4
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	77kDa
Manufacturer - Research Areas	Cancer, Neuroscience
Background	The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
Concentration	0.9 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:200-1:1000; IHC 1:50-1:200
Santa Cruz #	sc-12442, sc-20882, sc-50417
Abbreviation	KCNQ4
Clonality	Polyclonal
Immunogen	Synthetic peptide of human KCNQ4
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.