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CDC42 Polyclonal Antibody

CDC42 Polyclonal Antibody

Item no.	E-AB-60243-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 200 uL 60 uL
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot Primary Antibodies small GTPases Rho Subfamily
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CDC42, CDC42Hs, G25K, TKS
Similar products	CDC42Hs, CDC42, G25K, dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)), Cell division control protein 42 homolog, Cell division cycle 42, Growth regulating protein, G25K GTP-binding protein, dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, Cell division cycle 42 (GTP binding protein 25kDa), GTP binding protein 25kDa, Small GTP binding protein CDC42, TKS
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CDC42
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	21kDa
Observed Molecular Weight	21kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction
Background	The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	IHC 1:50-1:200
Abbreviation	CDC42
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human CDC42 (NP_001782.1).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.