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CBS Polyclonal Antibody

CBS Polyclonal Antibody

Item no.	E-AB-60308-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 200 uL 60 uL
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot Immunofluorescence Enzymes Prostaglandin Synthases Primary Antibodies
Type	Antibody Polyclonal
Applications	IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CBS, HIP4
Similar products	CBS, Cbs, HIP4, OTTHUMP00000109416, OTTHUMP00000109418, Beta thionase, Beta-thionase, Cystathionine beta synthase, Cystathionine beta-synthase, HIP 4, Methylcysteine synthase, Serine sulfhydrase, AI047524, AI303044, Cbs cystathionine beta-synthase, EC 4.2.1.22, MGC18856, MGC18895, MGC37300
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CBS
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	60kDa/61kDa
Observed Molecular Weight	61kDa
Manufacturer - Research Areas	Cancer, Metabolism, Signal Transduction
Background	The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	IF 1:50-1:200
Abbreviation	CBS
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human CBS (NP_000062.1).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.