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AIRE Polyclonal Antibody

AIRE Polyclonal Antibody

Item no.	E-AB-60437-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 200 uL 60 uL
Category	Neuroscience Targets for Rodent Neurosciences Antibodies Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AIRE, AIRE1, APECED, APS1, APSI, PGA1
Similar products	APECED, AIRE, APS1, AIRE1, APSI, PGA1, Autoimmune regulator, APECED protein, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator protein
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	AIRE
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	25kDa/35kDa/36kDa/57kDa
Observed Molecular Weight	55kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling, Immunology
Background	This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	IF 1:50-1:200
Abbreviation	AIRE
Clonality	Polyclonal
Immunogen	A synthetic peptide of human AIRE (NP_000374.1).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.