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(KO Validated) SMARCA4 Polyclonal Antibody

(KO Validated) SMARCA4 Polyclonal Antibody

Item no.	E-AB-60619-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 200 uL 60 uL
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Movement Mesothelioma Western Blot Immunofluorescence Cardiovascular Research Myocardial Infarction Primary Antibodies Cell Migration & Invasion
Type	Antibody Polyclonal
Applications	IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BAF190, BAF190A, BRG1, CSS4, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b, SMARCA4
Similar products	SMARCA4, SNF2LB, SWI2, member 4, SWI/SNF related, matrix associated, BAF190, SNF2, BRG1, SNF2L4, hSNF2b, ATP-dependent helicase SMARCA4, actin dependent regulator of chromatin, SMCA4, subfamily a, Global transcription activator homologous sequence, ATP dependent helicase SMARCA4, BAF 190, BAF190A, Brahma protein like 1, BRG1 associated factor 190A, BRG1 protein, BRM/SWI2 related gene 1, Homeotic gene regulator, Mitotic growth and transcription activator, Nuclear protein GRB1, Protein brahma homolog 1, Protein BRG1, SMARC A4, SNF2 beta, SNF2 like 4, SNF2B, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4, Transcription activator BRG1, BRG1-associated factor 190A, Protein BRG-1
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	SMARCA4
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	181kDa/184kDa
Observed Molecular Weight	190kDa
Manufacturer - Research Areas	Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Stem Cells
Background	The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	IF 1:50-1:200
Abbreviation	SMARCA4
Clonality	Polyclonal
Immunogen	A synthetic peptide of human SMARCA4 (NP_003063.2).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.