OPRL1 Polyclonal Antibody

H.sapiens mRNA for ORL1 receptor, Kappa type 3 opioid receptor, Kappa-type 3 opioid receptor, kappa3-related opioid receptor, KOR 3, KOR-3, KOR3, LC132 receptor like, LC132 receptor, rat, homolog of, MGC34578, Nociceptin receptor, Nociceptin/orphanin FQ (N/OFQ) peptide receptor, NOCIR, NOP, OOR, Opiate receptor like 1, Opiod receptor like 1, Oprl1, OPRX, ORL1, Orphanin FQ receptor

The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

WB 1:500 - 1:2000

40kDa