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Crystallin-alpha C Polyclonal Antibody

Crystallin-alpha C Polyclonal Antibody

Item no.	E-AB-10378-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry ELISA Primary Antibodies By Organ Breast Cancer
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Alpha crystallin C chain, Alpha-crystallin C chain, Charcot Marie Tooth disease axonal type 2L, Charcot Marie Tooth disease spinal, CMT2L, CRYAC, DHMN 2, DHMN2, E2 induced gene 1 protein, E2-induced gene 1 protein, E2IG1, H11, Heat shock 22kDa protein 8, Heat shock 27kDa protein 8, Heat shock protein 22, Heat shock protein beta 8, Heat shock protein beta-8, Hereditary motor neuropathy distal, HMN 2, HMN2, HMN2A, HSB8, HSPB 8, Hspb8, HSPB8, OTTHUMP00000239768, Protein kinase H11, Small stress protein like protein HSP22, Small stress protein-like protein HSP22, Spinal muscular atrophy distal adult autosomal dominant
Similar products	HSPB8, Hspb8, CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, CRYAC, DHMN 2, E2 induced gene 1 protein, Heat shock 22kDa protein 8, Heat shock protein 22, Heat shock protein beta 8, Hereditary motor neuropathy distal, HMN 2, HSB8, HSPB 8, Protein kinase H11, Small stress protein like protein HSP22, Spinal muscular atrophy distal adult autosomal dominant, Alpha crystallin C chain, Charcot Marie Tooth disease axonal type 2L, Heat shock protein beta-8, Alpha-crystallin C chain, E2-induced gene 1 protein, Heat shock 27kDa protein 8, Small stress protein-like protein HSP22, Charcot Marie Tooth disease spinal, OTTHUMP00000239768
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	HSPB8
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	Cancer, Neuroscience, Signal Transduction
Background	The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Concentration	0.3 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	IHC 1:50-1:200
Santa Cruz #	sc-22393
Abbreviation	HSPB8
Clonality	Polyclonal
Immunogen	Recombinant protein of human HSPB8
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.