ACLY Polyclonal Antibody

ACLY

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440, 000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

ACLY

Recombinant protein of human ACLY