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PRMT5 Polyclonal Antibody

PRMT5 Polyclonal Antibody

Item no.	E-AB-12625-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies Western Blot ELISA Primary Antibodies By Organ Lung Cancer Colorectal Cancer Testicular & Prostate Cancer Astrocyte Markers
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	72 kDa ICln binding protein, 72 kDa ICln-binding protein, ANM5, Histone synthetic lethal 7, S. cerevisiae, homolog of, Histone-arginine N-methyltransferase PRMT5, HMT1 hnRNP methyltransferase like 5, HOMOLOG OF, SKB1, HRMT1L5, IBP72, Jak-binding protein 1, JBP 1, JBP1, PRMT 5, PRMT5, Protein arginine methyltransferase 5, Protein arginine N methyltransferase 5, Protein arginine N methyltransferase 5 N terminally processed, Protein arginine N-methyltransferase 5, S. POMBE, S. POMBE HOMOLOG OF, SKB1, SHK1 KINASE BINDING PROTEIN 1, Shk1 kinase binding protein 1 homolog, Shk1 kinase-binding protein 1 homolog, Shk1 kinase/binding protein 1, S. pombe, homolog of, SKB 1, SKB1, SKB1 homolog, SKB1: SKB1 homolog (S. pombe), SKB1Hs
Similar products	PRMT5, HRMT1L5, IBP72, JBP1, SKB1, Protein arginine N-methyltransferase 5, 72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Shk1 kinase-binding protein 1 homolog, S. cerevisiae, homolog of, S. pombe, SKB1Hs, SKB1 homolog, ANM5, HOMOLOG OF, 72 kDa ICln binding protein, HMT1 hnRNP methyltransferase like 5, JBP 1, PRMT 5, Protein arginine methyltransferase 5, Protein arginine N methyltransferase 5, S. POMBE, S. POMBE HOMOLOG OF, SHK1 KINASE BINDING PROTEIN 1, Shk1 kinase binding protein 1 homolog, SKB 1, Histone synthetic lethal 7, Protein arginine N methyltransferase 5 N terminally processed, Shk1 kinase/binding protein 1, SKB1: SKB1 homolog (S. pombe)
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	PRMT5
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	71kDa
Manufacturer - Research Areas	Cancer, Epigenetics and Nuclear Signaling
Background	Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation.
Concentration	0.3 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:200-1:1000
Santa Cruz #	sc-22132, sc-136202, sc-292408
Abbreviation	PRMT5
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PRMT5
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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