APBA1 Polyclonal Antibody

Adapter protein X11 alpha, Adapter protein X11alpha, Amyloid beta A4 precursor protein-binding family A member 1, Apba1, APBA1, Mint 1, Mint-1, Neuron specific X11 protein, Neuron-specific X11 protein, Neuronal Munc18 1 interacting protein 1, Neuronal Munc18-1-interacting protein 1, UROP11, x11, X11alpha

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

WB 1:500-1:2000

93kDa

sc-18332, sc-14032