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MT-ND1 Polyclonal Antibody

MT-ND1 Polyclonal Antibody

Item no.	E-AB-13427-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Complex I, subunit ND1, Mitochondrially encoded NADH dehydrogenase 1, MT-ND1, MTND1, NAD1, NADH dehydrogenase subunit 1 (complex I), NADH dehydrogenase subunit 1, NADH-ubiquinone oxidoreductase chain 1, NADH-ubiquinone oxidoreductase, subunit ND1, NADH1, ND1, NU1M
Similar products	MTND1, MT-ND1, ND1, NADH dehydrogenase subunit 1, NADH-ubiquinone oxidoreductase, NU1M, Complex I, Mitochondrially encoded NADH dehydrogenase 1, NAD1, NADH1, NADH-ubiquinone oxidoreductase chain 1, subunit ND1, NADH dehydrogenase subunit 1 (complex I)
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	MT-ND1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	36kDa
Research Areas	Cancer, Metabolism, Signal Transduction
Background	NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.
Concentration	1 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:200-1:1000; IHC 1:50-1:200
Abbreviation	MT-ND1
Clonality	Polyclonal
Immunogen	Synthetic peptide of human MT-ND1
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.