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PKM Polyclonal Antibody

PKM Polyclonal Antibody

Item no.	E-AB-13771-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Metabolism Glucose Homeostasis Assisted reproductive technologies Embryo manipulation Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Thyroid Cancer
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CTHBP, Cytosolic thyroid hormone binding protein, Cytosolic thyroid hormone-binding protein, KPYM, MGC3932, OIP 3, OIP-3, OIP3, OPA interacting protein 3, Opa-interacting protein 3, p58, PK muscle type, PK, muscle type, PK2, PK3, PKM, PKM2, pykm, Pyruvate kinase 2/3, Pyruvate kinase 3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Pyruvate kinase muscle isozyme, pyruvate kinase PKM, Pyruvate kinase, muscle 2, TCB, THBP1, Thyroid hormone binding protein 1, Thyroid hormone binding protein cytosolic, Thyroid hormone-binding protein 1, Tumor M2 PK, Tumor M2-PK
Similar products	PKM2, PKM, OIP3, PK2, PK3, Pyruvate kinase isozymes M1/M2, Cytosolic thyroid hormone-binding protein, Opa-interacting protein 3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, Tumor M2-PK, p58, muscle type, PK, CTHBP, MGC3932, TCB, THBP1, OIP-3, Cytosolic thyroid hormone binding protein, OIP 3, OPA interacting protein 3, Pyruvate kinase 3, Pyruvate kinase muscle, Thyroid hormone binding protein cytosolic, Pyruvate kinase, Tumor M2 PK, KPYM, PK muscle type, pykm, pyruvate kinase PKM, muscle 2, Thyroid hormone binding protein 1
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	PKM2
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	58kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Background	This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Concentration	0.6 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:50-1:200
Abbreviation	PKM2
Clonality	Polyclonal
Immunogen	Recombinant protein of human PKM2
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.