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CALR Polyclonal Antibody

CALR Polyclonal Antibody

Item no.	E-AB-14113-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Antibodies By Cell Type Hematology Leukemia Cell Biology Cytoskeleton Myelofibrosis Immunohistochemistry Western Blot ELISA Primary Antibodies small GTPases Arf Subfamily
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Autoantigen RO, CALR, CALR protein, CALR, Calregulin, Calreticulin, cC1qR, CRP55, CRT, CRTC, Endoplasmic reticulum resident protein 60, Epididymis secretory sperm binding protein Li 99n, ERp60, FLJ26680, grp60, HACBP, HEL S 99n, RO, Sicca syndrome antigen A (autoantigen Ro, calreticulin), Sicca syndrome antigen A, SSA
Similar products	SSA, Calreticulin, CALR, CRT, FLJ26680, RO, cC1qR, Sicca syndrome antigen A (autoantigen Ro, calreticulin), ERp60, Sicca syndrome antigen A, CRP55, Calregulin, HACBP, CRTC, Endoplasmic reticulum resident protein 60, grp60, Autoantigen RO, CALR protein, Epididymis secretory sperm binding protein Li 99n, HEL S 99n
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CALR
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	48kDa
Manufacturer - Research Areas	Cancer, Signal Transduction, Tags and Cell Markers
Background	Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element.
Concentration	0.2 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:1000-1:5000; IHC 1:50-1:200
Santa Cruz #	sc-7431, sc-6468, sc-6467, sc-11398
Abbreviation	CALR
Clonality	Polyclonal
Immunogen	Recombinant protein of human CALR
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.