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ACTN4 Polyclonal Antibody

ACTN4 Polyclonal Antibody

Item no.	E-AB-14759-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Movement Immunohistochemistry Western Blot ELISA Primary Antibodies Cell Migration & Invasion By Organ Skin Cancer Cytoskeleton Markers
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	actinin 4, Actinin alpha 4, actinin4, ACTN 4, ACTN4, ACTN4, Alpha-actinin-4, DKFZp686K23158, F actin cross linking protein, F-actin cross-linking protein, Focal segmental glomerulosclerosis 1, FSGS 1, FSGS, FSGS1, Non muscle alpha actinin 4, Non-muscle alpha-actinin 4
Similar products	Alpha-actinin-4, ACTN4, F-actin cross-linking protein, DKFZp686K23158, FSGS, FSGS1, Actinin alpha 4, actinin 4, actinin4, ACTN 4, F actin cross linking protein, FSGS 1, Non-muscle alpha-actinin 4, Focal segmental glomerulosclerosis 1, Non muscle alpha actinin 4
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	ACTN4
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	105kDa
Research Areas	Cancer, Metabolism, Signal Transduction
Background	Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.
Concentration	0.8 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:50-1:200
Santa Cruz #	sc-49332, sc-49333, sc-7453, sc-135346, sc-15335, sc-7454-R
Abbreviation	ACTN4
Clonality	Polyclonal
Immunogen	Recombinant protein of human ACTN4
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.