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KCNQ1 Polyclonal Antibody

KCNQ1 Polyclonal Antibody

Item no.	E-AB-15154-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Neuroscience Neural Transcription Factors Antibodies Immunohistochemistry Western Blot ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ATFB1, ATFB3, FLJ26167, IKs producing slow voltage-gated potassium channel subunit alpha, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, Jervell and Lange-Nielsen syndrome 1, JLNS1, KCNA8, KCNA9, KCNQ1, KCNQ1, kidney and cardiac voltage dependend K+ channel, KQT-like 1, Kv1.9, Kv7.1, KVLQT1, long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1, LQT, LQT1, Potassium channel, voltage-gated, shaker-relatd subfamily, member 9, Potassium voltage-gated channel subfamily KQT member 1, potassium voltage-gated channel, KQT-like subfamily, member 1, RWS, slow delayed rectifier channel subunit, SQT2, Voltage-gated potassium channel subunit Kv7.1, WRS
Similar products	KCNQ1, Potassium channel, KCNA8, KCNA9, KVLQT1, Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv7.1, WRS, member 1, member 9, potassium voltage-gated channel, voltage-gated, ATFB1, ATFB3, FLJ26167, JLNS1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, kidney and cardiac voltage dependend K+ channel, slow delayed rectifier channel subunit, IKs producing slow voltage-gated potassium channel subunit alpha, Jervell and Lange-Nielsen syndrome 1, long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1, shaker-relatd subfamily, KQT-like subfamily
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	KCNQ1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	75kDa
Manufacturer - Research Areas	Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
Background	This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
Concentration	0.2 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:200-1:1000; IHC 1:50-1:200
Santa Cruz #	sc-10645, sc-10646, sc-20816
Abbreviation	KCNQ1
Clonality	Polyclonal
Immunogen	Recombinant protein of human KCNQ1
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.