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MECP2 Polyclonal Antibody

MECP2 Polyclonal Antibody

Item no.	E-AB-15195-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Epigenetics Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Glial Cell Markers
Type	Antibody Polyclonal
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AUTSX 3, AUTSX3, DKFZp686A24160, Mbd 5, Mbd5, MECP 2, MeCP 2 protein, MeCP-2 protein, Mecp2, MECP2, Methyl CpG binding protein 2 (Rett syndrome), Methyl CpG binding protein 2, Methyl-CpG-binding protein 2, MRX 16, MRX 79, MRX16, MRX79, MRXS 13, MRXS13, MRXSL, PPMX, RS, RTS, RTT, WBP 10, WBP10
Similar products	MECP2, Methyl-CpG-binding protein 2, RTS, Mecp2, Mbd5, RS, AUTSX3, DKFZp686A24160, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTT, AUTSX 3, Mbd 5, MECP 2, MeCP 2 protein, Methyl CpG binding protein 2, MRX 16, MRX 79, MRXS 13, WBP 10, MeCP-2 protein, Methyl CpG binding protein 2 (Rett syndrome), WBP10
Shipping Condition	Cool pack
Available
Manufacturer - Category	Polyclonal Antibody
Shipping Temperature	Biological Ice Packs
Storage Conditions	-20°C for 12 months
Calculated Molecular Weight	52kDa
Manufacturer - Research Areas	Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Background	DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development.
Concentration	0.5 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, pH 7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:200-1:1000, IHC 1:100-1:300
Santa Cruz #	sc-5758, sc-5755, sc-20700
Clonality	Polyclonal
Immunogen	Recombinant protein of human MECP2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.