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GRK2 Polyclonal Antibody

GRK2 Polyclonal Antibody

Item no.	E-AB-31617-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Obesity Immunohistochemistry Western Blot ELISA Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ADRBK1, Adrenergic beta receptor kinase 1, ARBK1, BARK, BARK1, Beta adrenergic receptor kinase 1, Beta ARK 1, Beta ARK1, Beta-adrenergic receptor kinase 1, Beta-ARK-1, FLJ16718, G protein coupled receptor kinase 2, G-protein coupled receptor kinase 2, GRK2
Similar products	Beta-ARK-1, ADRBK1, GRK2, BARK1, FLJ16718, ARBK1, G-protein coupled receptor kinase 2, Adrenergic beta receptor kinase 1, BARK, Beta adrenergic receptor kinase 1, Beta ARK 1, Beta ARK1, Beta-adrenergic receptor kinase 1, G protein coupled receptor kinase 2
Available
Storage Conditions	Store at -20C. Avoid freeze / thaw cycles.
Calculated Molecular Weight	80kDa
Observed Molecular Weight	80kDa
Research Areas	Cancer, Neuroscience, Signal Transduction
Background	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Immunogen	Synthesized peptide derived from the C-terminal region of human GRK 2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 120 uL

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Delivery expected until 9/11/2025

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