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FLNA Polyclonal Antibody

FLNA Polyclonal Antibody

Item no.	E-AB-62082-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 200 uL 60 uL
Category	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Movement Obesity Immunohistochemistry Western Blot Cardiovascular Research Thrombosis & Hemostasis Atherosclerosis Primary Antibodies Cell Migration & Invasion Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, filamin-A
Similar products	Filamin A, FLNA, Alpha-filamin, Filamin-1, Endothelial actin-binding protein, Actin-binding protein 280, ABP-280, Non-muscle filamin, FLN, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, ABP 280, Alpha filamin, APBX, Endothelial actin binding protein, Filamin 1, Filamin-A, FLN-A, Non muscle filamin, XMVD, CVD1, XLVD, CSBS, Filamin A alpha
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	FLNA
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	280kDa
Observed Molecular Weight	281kDa
Manufacturer - Research Areas	Cancer, Signal Transduction
Background	The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	IHC 1:50-1:200
Abbreviation	FLNA
Clonality	Polyclonal
Immunogen	A synthetic peptide of human FLNA (NP_001104026.1).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.