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PRKAB1 Polyclonal Antibody

PRKAB1 Polyclonal Antibody

Item no.	E-AB-62178-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 200 uL 60 uL
Category	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Neural Signaling Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Cell Biology Obesity Cell Status Immunohistochemistry Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PRKAB1, AMPK, HAMPKb
Similar products	PRKAB1, AMPK, protein kinase, beta-1, HAMPKb, AMPK subunit beta-1, AMPKb, AMPK beta 1 chain, AMP-activated protein kinase beta subunit, AMP-activated, noncatalytic, 5'-AMP-activated protein kinase beta-1 subunit, 1300015D22Rik, 5''-AMP-activated protein kinase subunit beta-1, AAKB1, AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1, AMPK-BETA-1, AU021155, E430008F22, MGC17785, Protein kinase AMP activated non catalytic subunit beta 1, beta 1 non-catalytic subunit
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	PRKAB1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	30kDa
Observed Molecular Weight	37kDa
Manufacturer - Research Areas	Cancer, Cardiovascular, Metabolism, Signal Transduction
Background	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	IHC 1:50-1:200
Abbreviation	PRKAB1
Clonality	Polyclonal
Immunogen	A synthetic peptide of human PRKAB1
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.