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COASY Polyclonal Antibody

COASY Polyclonal Antibody

Item no.	E-AB-63652-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 200 uL 60 uL
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot Enzymes Prostaglandin Synthases Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	COASY, DPCK, NBIA6, NBP, PPAT, UKR1, pOV-2
Similar products	COASY, PPAT, NBP, DPCK, UKR1, Bifunctional coenzyme A synthase, Bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase, CoA synthase, Coenzyme A synthase, Dephospho-CoA kinase, Dephospho-CoA pyrophosphorylase, Dephosphocoenzyme A kinase, DPCOAK, Nucleotide binding protein, Pantetheine-phosphate adenylyltransferase, Phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase, pOV 2, POV-2, POV2
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	COASY
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	62kDa/65kDa
Observed Molecular Weight	62kDa
Research Areas	Cancer, Metabolism, Signal Transduction
Background	Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000
Abbreviation	COASY
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human COASY (NP_079509.5).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.