CD3D Polyclonal Antibody

CD3D

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

19kDa

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IHC 1:50-1:100; IF 1:50-1:100

Polyclonal

Polyclonal Antibodies