Similar products |
SERPINF2, Alpha 2 antiplasmin, API, member 2, A2AP, AAP, PLI, isoform CRA_c, Serpin peptidase inhibitor, Alpha 2 antiplasmin pigment epithelium derived factor, Alpha 2 AP, ALPHA 2 PI, Alpha 2 plasmin inhibitor, Alpha 2 plasmin inhibitor deficiency, Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-PI, Alpha-2-plasmin inhibitor, Antiplasmin deficiency, Plasmin inhibitor deficiency, clade F, Serine or cysteine peptidase inhibitor clade F member 2, Serpin F2, Serpin peptidase inhibitor clade F, Serine (or cysteine) proteinase inhibitor, Serine (or cysteine) peptidase inhibitor, Serine (Or cysteine) peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2, Serine (Or cysteine) proteinase inhibitor |
Background |
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. |