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FMR1 Polyclonal Antibody

FMR1 Polyclonal Antibody

Item no.	E-AB-63843-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 200 uL 60 uL
Category	Neuroscience Neural Transcription Factors Molecular Targets for Neuroscience Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FMRP, FRAXA, POF, POF1, FMR1, POFX
Similar products	FMR1, Fmr1, Fragile X mental retardation protein 1, POF1, fxr1, POF, FMRP, FRAXA, MGC87458, FMR 1, Fragile X mental retardation 1, Fragile X mental retardation 1 protein, Protein FMR-1, Fmr1 gene, Fragile X mental retardation protein, fragile X mental retardation syndrome-related protein 1, fragile X mental retardation, autosomal homolog 1, Protein FMR1, wu:fb16f11, wu:fd18c10, zgc:66226
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	FMR1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	58kDa/61kDa/66kDa/68kDa/69kDa/70kDa/71kDa
Observed Molecular Weight	71kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Background	The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:1000; IHC 1:50-1:200
Abbreviation	FMR1
Clonality	Polyclonal
Immunogen	A synthetic peptide of human FMR1 (NP_002015.1).
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.