NMNAT1 Polyclonal Antibody

Polyclonal Antibody

-20°C for 12 months

28kDa

This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.

PBS with 0.01% thiomersal, 50% glycerol, pH 7.3.

WB1:500 - 1:2000

Recombinant fusion protein of human NMNAT1