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XRCC4 Monoclonal Antibody

XRCC4 Monoclonal Antibody

Manufacturer	Elabscience
Category	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human
Clone	8K2
Isotype	IgG
Applications	WB, IF, IP, IHC-P
Amount	60uL
Host	Mouse
Item no.	E-AB-22044-60
eClass 6.1	32160702
eClass 9.0	42030590
Available
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Synonyms	DNA double strand break repair and V(D)J recombination protein XRCC4, DNA repair protein XRCC4, SSMED, X ray repair complementing defective repair in Chinese hamster cells 4, X ray repair cross complementing 4, X ray repair cross complementing protein 4, X-ray repair cross-complementing protein 4, XRCC 4, XRCC4, XRCC4
Swissprot	Q13426
Background	Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Concentration	1 mg/mL
Storage	Store at -20C. Avoid freeze / thaw cycles.
Immunogen	Synthetic Peptide
Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method	Protein A purification
Dilution	WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Conjugation	Unconjugated
Calculated MW	38kDa
Observed MW	38kDa
Santa Cruz #	sc-136124, sc-365055, sc-365118

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 60uL

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Delivery expected until 7/11/2024