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CASP10 B/C Polyclonal Antibody

CASP10 B/C Polyclonal Antibody

Item no.	E-AB-30753-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Applications	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALPS2, apoptotic protease Mch-4, CASP-10, CASPA, caspase-10, FADD-like ICE2, FAS-associated death domain protein interleukin-1B-convert
Similar products	caspase-10, ALPS2, FADD-like ICE2, CASPA, CASP-10, apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-convert
Available
Storage Conditions	Store at -20C. Avoid freeze / thaw cycles.
Calculated Molecular Weight	59kDa
Observed Molecular Weight	60kDa
Research Areas	Cancer, Cell Biology, Metabolism
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-AMC and Asp-Glu-Val-Asp-AMC.Isoform C is proteolytically inactive.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Immunogen	Synthesized peptide derived from the C-terminal region of human Caspase-10 B/C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 uL

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Delivery expected until 9/11/2025

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