« Back
Home /
Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody

Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody

Item no.	E-AB-20966-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Cardiovascular Research Proliferation Myocardial Infarction Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://elifesciences.org/articles/79590 https://www.mdpi.com/1281194
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GRB1, p85 alpha, p85, P85A, Phosphatidylinositol 3 kinase associated p 85 alpha, Phosphatidylinositol 3 kinase regulatory 1, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphoinositide 3 kinase, regulatory subunit 1 (alpha), PI3 kinase p85 subunit alpha, PI3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PI3K, PI3K regulatory subunit alpha, Pik3r1, PtdIns 3 kinase p85 alpha, PtdIns-3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit p85-alpha
Similar products	Pik3r1, p85, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, GRB1, PI3K, regulatory subunit, polypeptide 1 (p85 alpha), P85A, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, p85 alpha, Phosphatidylinositol 3 kinase regulatory 1, PI3 kinase p85 subunit alpha, Phosphatidylinositol 3 kinase, Phosphoinositide 3 kinase, Phosphatidylinositol 3 kinase associated p 85 alpha, regulatory subunit 1 (alpha), PtdIns 3 kinase p85 alpha
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	PI 3-kinase p85/p55 (phospho Tyr467/199)
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	54+83kDa
Observed Molecular Weight	55+85kDa
Manufacturer - Research Areas	Cancer, Immunology, Signal Transduction
Background	The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Abbreviation	PI 3-kinase p85/p55 (phospho Tyr467/199)
Clonality	Polyclonal
Immunogen	Synthesized peptide derived from human PI 3-kinase p85/p55 around the phosphorylation site of Tyr467/199
Category ID III	Acetyl/Phospho/Methyl Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.