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SIRT1 Polyclonal Antibody

SIRT1 Polyclonal Antibody

Item no.	E-AB-32901-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Hematology Myeloma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://link.springer.com/article/10.1007/s12079-022-00703-0
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	75SirT1, hSIR2, hSIRT1, HST2, S. cerevisiae, homolog of, NAD dependent deacetylase sirtuin 1, NAD dependent protein deacetylase sirtuin 1, OTTHUMP00000198111, OTTHUMP00000198112, Regulatory protein SIR2 homolog 1, SIR1, SIR2, SIR2 like 1, SIR2 like protein 1, SIR2, S.cerevisiae, homolog-like 1, SIR2-like protein 1, SIR2ALPHA, SIR2L1, Sirt1, SirtT1 75 kDa fragment, Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), Sirtuin 1, Sirtuin type 1
Similar products	HST2, SIR2, Sirt1, S. cerevisiae, homolog of, S.cerevisiae, homolog-like 1, SIR2L1, Sirtuin 1, hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, 75SirT1, NAD dependent deacetylase sirtuin 1, OTTHUMP00000198111, OTTHUMP00000198112, SIR2 like 1, SIR2 like protein 1, SIR2ALPHA, SirtT1 75 kDa fragment, Sirtuin type 1, SIR1, NAD dependent protein deacetylase sirtuin 1, Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	SIRT1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	82kDa
Observed Molecular Weight	81kDa-120kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Tags and Cell Markers
Background	This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins witHuman, Mouseono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:50-1:200
Santa Cruz #	sc-19858, sc-19857, sc-15404
Abbreviation	SIRT1
Clonality	Polyclonal
Immunogen	Synthesized peptide derived from human SIRT1 around the non-phosphorylation site of Ser47.
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.