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Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody

Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody

Item no.	E-AB-21027-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neural Lineage Markers Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Glial Cell Markers
Type	Antibody Polyclonal
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-023-01803-8 https://onlinelibrary.wiley.com/doi/abs/10.1111/cpr.13351 https://www.sciencedirect.com/science/article/pii/S0753332223000823 https://www.mdpi.com/1281194 https://link.springer.com/article/10.1007/s12079-022-00703-0 https://link.springer.com/article/10.1186/s12935-022-02503-3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364650/ https://www.mdpi.com/2076-3921/9/1/37/htm https://pubs.acs.org/doi/abs/10.1021/acs.jafc.8b07227 https://www.sciencedirect.com/science/article/pii/S1567576918312372 https://onlinelibrary.wiley.com/doi/abs/10.1111/exd.14041 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201345/
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CSAID Binding Protein 1, CSAID binding protein, CSAID-binding protein, Csaids binding protein, CSBP 1, CSBP 2, CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, MAX-interacting protein 2, Mitogen Activated Protein Kinase 14, Mitogen activated protein kinase p38 alpha, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, MK14, Mxi 2, MXI2, p38 ALPHA, p38, p38 MAP kinase, p38 MAPK, p38 mitogen activated protein kinase, p38ALPHA, p38alpha Exip, PRKM14, PRKM15, RK, SAPK2A
Similar products	p38 MAPK, MAPK14, p38, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, RK, CSBP, CSBP1, CSBP2, CSPB1, EXIP, PRKM14, PRKM15, SAPK2A, p38ALPHA, Csaids binding protein, MAX-interacting protein 2, MK14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, MAP kinase MXI2, MAP kinase p38 alpha, CSAID Binding Protein 1, CSAID binding protein, CSBP 1, CSBP 2, MAX interacting protein 2, Mitogen Activated Protein Kinase 14, Mitogen activated protein kinase p38 alpha, Mxi 2, p38 ALPHA, p38 MAP kinase, p38 mitogen activated protein kinase, p38alpha Exip
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	p38 (phospho Thr180/Tyr182)
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	41kDa
Observed Molecular Weight	38kDa
Research Areas	Cancer, Immunology, Signal Transduction
Background	MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:50-1:200
Santa Cruz #	sc-535, sc-7149, sc-728
Abbreviation	p38 (phospho Thr180/Tyr182)
Clonality	Polyclonal
Immunogen	Synthesized peptide derived from human p38 around the phosphorylation site of Thr180/Tyr182
Category ID III	Acetyl/Phospho/Methyl Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.