ClinMax™ Human Interleukin 4 (IL-4) Quantitative ELISA Kit

CRS Related Kits

ClinMax™Human IL-4 Quantitative ELISA Kit is designed to quantitate human IL-4 that is present in complex biological matrices, such as human serum, plasma, buffered solution, or cell culture.
IL-4 is a cytokine with pleiotropic functions. IL-4 plays a key role in the development of Th2 responses. In mice that lack IL-4, there is significant abrogation of Th2 cellular activity. IL-4 promotes the growth and activation of B lymphocytes that produce IgG1 and IgE classes of antibodies and increases MHC class II induction. Preclinical animal models have demonstrated modest antitumor efficacy for IL-4. In the nonimmunogenic B16 murine melanoma model, irradiated B16 cells engineered to express IL-4 induced antitumor protection against a wild-type B16 challenge.