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FGA ELISA Kit (Bovine)

FGA ELISA Kit (Bovine)

Item no.	OKEH03913
Manufacturer	AVIVA Systems Biology
Amount	96 Wells
Category	Neuroscience Neuroinflammation Neural Signaling Neural Adhesion Molecules Cell Biology Cell Culture Cytokines ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Specific against	Cattle (Bovine)
Sensitivity	3 ng/mL
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Fibrinogen alpha chain
Shipping Condition	Cool pack
Available
Manufacturer - Type	ELISA Kit
Manufacturer - Category	Root Catalog/Products/ELISA Kits, Root Catalog/Products/Kit
Shipping Temperature	Wet Ice
Molecular Weight	615 kDa
Gene symbol	FGA
Gene Fullname	fibrinogen alpha chain
Protein size	615
Reconstitution and storage	Store as indicated in product manual.
Description of target	Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Nucleotide accession_num	NM_001033626.1
Protein accession_num	NP_001028798.1
Protein name	Fibrinogen alpha chain
Manufacturer - Specificity	Natural and recombinant Bovine Fibrinogen alpha chain
Assay info	Assay Methodology: Quantitative Sandwich ELISA
Kit duration	~ 3 Hours
Kit principle	Aviva Systems Biology FGA ELISA Kit (Bovine) (OKEH03913) is based on standard sandwich enzyme-linked immuno-sorbent assay technology. An antibody specific for FGA has been pre-coated onto a 96-well plate (12 x 8 Well Strips) and blocked. Standards or test samples are added to the wells, incubated and removed. A biotinylated detector antibody specific for FGA is added, incubated and followed by washing. Avidin-Peroxidase Conjugate is then added, incubated and unbound conjugate is washed away. An enzymatic reaction is produced through the addition of TMB substrate which is catalyzed by HRP generating a blue color product that changes yellow after adding acidic stop solution. The density of yellow coloration read by absorbance at 450 nm is quantitatively proportional to the amount of sample FGA captured in well.
Sample Type	Serum, Plasma, Tissue Homogenates , Cell Culture Supernates, Other Biological Fluids

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

OKEH03913.pdf

OKEH03913-datasheet.pdf

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Amount: 96 Wells

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Delivery expected until 10/30/2025

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