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Phospho-CCR5(Ser349) Antibody

Phospho-CCR5(Ser349) Antibody

Item no.	E18-0018-1
Manufacturer	Enogene
Amount	50 ug/50 ul
Quantity options	50 ug/50 ul 100 ug/100 ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies
Type	Antibody
Applications	WB
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein name C-C chemokine receptor type 5 , Synonyms C-C CKR-5, CC-CKR-5, , CCR-5, CCR5, HIV-1 fusion coreceptor, CHEMR13, CD195 antigen , Gene name Name: CCR5 , Synonyms: CMKBR5
Available
Specificity	Phospho-CCR5(Ser349) Antibody detects endogenous levels of CCR5 only when phosphorylated at Sersine 349
Manufacturer - Applications	WB 1:500-1:2000
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	40kDa
Immunogen	A synthesized peptide derived from human CCR5 around the phosphorylation site of Sersine 349
Purification	Immunogen affinity purified
Background	CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. Efficient ligand binding to CCL3/MIP-1alpha and CCR4/MIP-1beta requires sulfation, O-glycosylation and sialic acid modifications. Glycosylation on S6 is required for efficient binding of CCL4.
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0035208

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug/50 ul

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Delivery expected until 10/23/2025

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