Nucleophosmin Antibody

WB, IHC, IF, ELISA. Not yet tested in other applications.

Store at 4C, for long term storage, store at -20C.

Purified recombinant fragment of human NPM expressed in E. Coli.

Nucleophosmin (NPM), also named B23 or NO38, is a major nucleolar protein which is 20 times more abundant in tumor or proliferating cells than in normal resting cells. NPM has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.

Ascitic fluid containing 0.03% sodium azide.