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Bax Antibody

Bax Antibody

Item no.	E18-0083-2
Manufacturer	Enogene
Amount	100 ug/100 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 100 ug 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ug/100 ul 100 ug/100 ul 100 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Western Blot Immunofluorescence Immunocytochemistry Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Type	Antibody
Applications	WB, IF, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Apoptosis regulator BAX, BAX, Bcl-2-like protein 4, BCL2-associated X protein, Bcl2-L-4, BCL2L4
Available
Specificity	Bax antibody detects endogenous levels of total Bax
Manufacturer - Applications	WB: 1:500~1:3000 IF/ICC: 1:100~1:500
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	21kDa
Immunogen	A synthesized peptide derived from human Bax
Purification	Affinity-chromatography
Background	Bax Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Induces the release of cytochrome c, activation of CASP3, and thereby apoptosis. Belongs to the Bcl-2 family. Homodimer. Forms heterodimers with BCL2, E1B 19K protein, BCL2L1 isoform Bcl-X(L), MCL1 and A1. Interacts with SH3GLB1 and HN. Interacts with SFN and YWHAZ; the interaction occurs in the cytoplasm. Under stress conditions, JNK-mediated phosphorylation of SFN and YWHAZ, releases BAX to mitochondria. Isoform Sigma interacts with BCL2A1 and BCL2L1 isoform Bcl-X(L). 8 isoforms of the human protein are produced by alternative splicing.
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0035269

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/100 ul

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Delivery expected until 8/28/2025

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