MDM2 Antibody

Item no.	E18-0208-1
Manufacturer	Enogene
Amount	50 ug/50 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 100 ul 100 ul 100 ul 100 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ug/100 ul 200 ul 100 ug/200 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 50 ul 100 ug 100 ul
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Autophagy Primary Antibodies Astrocytoma By Organ Breast Cancer
Type	Antibody
Applications	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Double minute 2 protein, double minute 2, human homolog of, E3 ubiquitin-protein ligase Mdm2, Hdm2, HDMX, MDM2, Mdm2 p53 binding protein homolog (mouse), Mdm2, transformed 3T3 cell double minute 2, p53 binding protein, MGC5370, MGC71221, Oncoprotein Mdm2,
Available
Specificity	MDM2 antibody detects endogenous levels of total MDM2
Manufacturer - Applications	WB: 1:500~1:3000 IHC: 1:50~1:200 IF/ICC: 1:100~1:500
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	90kDa
Immunogen	A synthesized peptide derived from human MDM2
Purification	Affinity-chromatography
Background	MDM2 a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 via Akt-mediated MDM2 phosphorylation. Phosphorylation of MDM2 increases its interaction with p300, providing a platform to allow the assembly of the protein complex necessary for MDM2-mediated ubiquitination and degradation of p53. Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53. Facilitates the nuclear export of p53 and targets it for proteasome-mediated proteolysis. Eight alternatively spliced isoforms have been reported.
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, sodium azide and glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0035492

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug/50 ul

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Delivery expected until 10/23/2025

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