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CTNNB1 Antibody

CTNNB1 Antibody

Item no.	E19-6794
Manufacturer	Enogene
Amount	100 ug/100 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 100 ul 100 ul 100 ug/100 ul 50 ug 50 ug/50 ul 100 ug/100 ul 100 ug/200 ul 100 ul 100 ul 100 ul 100 ug
Category	Neuroscience Neural Adhesion Molecules Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CTNNB, DKFZp686D02253, FLJ25606, FLJ37923, ?-catenin,
Available
Specificity	CTNNB1 Antibody detects endogenous levels of total CTNNB1
Manufacturer - Applications	WB 1:500-1:2000 IHC 1:50-1:200
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	86kDa
Immunogen	A synthetic peptideof human CTNNB1
Purification	Immunogen affinity purified
Background	beta-Catenin is a key downstream effector in the Wnt signaling pathway (1). It is implicated in two major biological processes in vertebrates: early embryonic development (2) and tumorigenesis (3). CK1 phosphorylates beta-catenin at Ser45. This phosphorylation event primes beta-catenin for subsequent phosphorylation by GSK-3beta (4-6). GSK-3beta destabilizes beta-catenin by phosphorylating it at Ser33, Ser37, and Thr41 (7). Mutations at these sites result in the stabilization of beta-catenin protein levels and have been found in many tumor cell lines (8).
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0043071

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/100 ul

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Delivery expected until 1/22/2026

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