Rabbit Amyloid-Beta (1 - 40) ELISA Assay Kit, 96T

Manufacturer Fivephoton
Category Products / ELISA
Type Elisa-Kit
Specific against Rabbit
Amount 96T
ArtNr rbAB1-40ELISA
Eclass 6.1 32160605
Eclass 9.0 32160605
Available
Poisonous Material
Sodium Azide (0.1%)
Highlights
Colorimetric detection in sandwich ELISA format providing optimal convenience, specificity and sensitivity
Strip plate configuration allowing separate use and storage of ELISA plate sections
Affinity purified polyclonal capture antibody pre-coated on plate. Separate HRP-conjugated antibody used for detection
Rapid Assay: 2 hrs at RT
Suitable for CSF, other biological fluids, cell and tissue homogenates and lysates
ELISA kits are also available for human, canine, and rat Abeta 1-40
Background
Amyloid-Beta (Abeta) is generated by sequential cleavage of the amyloid precursor protein (APP) by beta and gamma secretases. The gamma secretase, which produces the C-terminal end of the Abeta peptide, cleaves within the transmembrane region of APP and generates amyloid-Beta (Abeta) isoforms of 36-43 amino acid residues in length. The predominant isoforms of amyloid-Beta are Abeta40 and Abeta42. The shorter amyloid-Beta isoform is typically produced by cleavage in the endoplasmic reticulum, while the longer isoform is processed by cleavage in the trans-Golgi network. Abeta40 is the most common amyloid-Beta (Abeta) isoform, but Abeta42 is more fibrillogenic and is thus the predominant form associated Alzheimer’s disease. Antibodies employed in this Amyloid-Beta ELISA kit are selective for the Abeta40 isoform of amyloid-beta, with insignificant cross-reactivity to the Abeta42 isoform.
Amount: 96T
Available: In stock
Listprice: €817.80
Discount: -10%
Price: €736.02
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