Comparison

Phosphatase Inhibitor Cocktail (100X; Broad Spectrum. Part No. PIC1; 5ml)

Manufacturer Fivephoton
Category
Type Inhibitors
Specific against other
Amount 5 ml (100X)
Item no. PIC1-5
eClass 6.1 30220300
eClass 9.0 32160605
Available
Poisonous Material
Harmful
Highlights
Available in 1 ml or 5 ml stock 100X water soluble phosphatse inhibitor cocktail solution.
Add directly to cell lysates or culture medium.
Broad spectrum, highly potent: Inhibits seryl, threonyl, tyrosyl, alkaline and Ca2+-phosphatases
Contains activated activated sodium orthovanadate, sodium tartrate, sodium fluoride, beta-glycerophosphate.
Ships at ambient temperature. Store at 4C short term (4 months) or -20C long term (2 years).
References
Arnold WN, Sakai KH, and Mann LC. Selective inactivation of an extra-cytoplasmic acid phosphatase of yeast-like cells of Sporothrix schenckii by sodium fluoride. J Gen Microbiol 133: 1503-1509, 1987.

Botana LM, Alfonso A, Botana MA, Vieytes MR, Louzao MC, and Cabado AG. Influence of protein kinase C, cAMP and phosphatase activity on histamine release produced by compound 48/80 and sodium fluoride on rat mast cells. Agents Actions 37: 1-7, 1992.

Gordon JA. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol 201: 477-482, 1991.

Guideri R, Cesari L, Burghesi R, and Medaglini E. [Behavior of calcemia, phosphoremia, calciuria, phosphaturia and alkaline phosphatase in normal subjects treated with sodium fluoride (NaF)]. Boll Soc Ital Biol Sper 42: 1612-1615, 1966.

Lange AJ, Arion WJ, Burchell A, and Burchell B. Aluminum ions are required for stabilization and inhibition of hepatic microsomal glucose-6-phosphatase by sodium fluoride. J Biol Chem 261: 101-107, 1986.

Li L, Eisen AZ, Sturman E, and Seltzer JL. Protein tyrosine phosphorylation in signalling pathways leading to the activation of gelatinase A: activation of gelatinase A by treatment with the protein tyrosine phosphatase inhibitor sodium orthovanadate. Biochim Biophys Acta 1405: 110-120, 1998.

Suketa Y, Kuwahara M, Sahashi K, Suzuki N, and Akiyama Y. A role of renal K+-stimulated phosphatase activity on elevation of urinary sodium excretion in fluoride-treated rats. Toxicol Appl Pharmacol 69: 225-233, 1983.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 ml (100X)
Available: In stock
available

Delivery expected until 5/2/2024 

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