Comparison

Mouse TNFSF15 Protein, Ultra Low Endotoxin (FSF-MM615-UL)

Item no. FSF-MM615-UL-500UG
Manufacturer KactusBio
Amount 500 ug
Quantity options 100 ug 500 ug
Category
Format Lyophilized
Specific against Mouse (Murine, Mus musculus)
Host HEK293
Conjugate/Tag Fc
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Sequence Ala61-Leu252
Alias TL1A,VEGI-251,TNFSF15,TL1,VEGI,VEGI192A
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
TNFSF15
Manufacturer - Conjugate / Tag
N-monomeric Fc
Shipping Temperature
Shipped at ambient temperature.
Storage Conditions
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Description
Recombinant Mouse TNFSF15 Protein is expressed from HEK293 with monomeric Fc tag at the N-terminus.It contains Ala61-Leu252.
Background
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or colitis and actively participate in the immunological pathways that underlie mucosal homeostasis and intestinal inflammation.Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation.
Endotoxin
Less than 0.01 EU per μg by the LAL method.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Biotinylated
no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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