EB1 Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-EB1 Polyclonal Antibody detects endogenous levels of human EB1. Positive Control: Hela and HEK293

EB1, also known as MAPRE1, is a regulator of microtubule dynamics that localizes at the growing plus ends of microtubules and the centrosome. It is important for anchoring cytoplasmic microtubule (MT) minus ends to the subdistal appendages of the mother centriole. EB1 plays a role in the regulation of MT dynamics and is implicated in regulation of cell polarity and chromosome stability. EB1 proteins interact physically with the adenomatous polyposis coli (APC) tumor suppressor protein, targeting APC to microtubule plus ends. GenScript, Rabbit Anti-EB1 Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide within residues 130-180 of human EB1 protein (Swiss Prot: Q15691).

Immunoaffinity chromatography.

Small volume of antibody will occasionally become entrapped in the cap of the vial during shipment and storage. Before use, centrifuge the vial briefly to bring down any liquid in the cap.