HDAC2 Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-HDAC2 Polyclonal Antibody detects endogenous levels of human HDAC2 protein.

HDAC2 (Histone deacetylase 2) belongs to the histone deacetylase family. Histone deacetylases are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3, and H4) via the formation of large multiprotein complexes. Histone deacetylation forms the tagging for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. HDAC2 also forms transcriptional repressor complexes by associating with many different proteins, such as YY1, a mammalian zinc-finger transcription factor. GenScript, Rabbit Anti-HDAC2 Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide derived from the carboxyl terminal residues of the human HDAC2 protein (Swiss Prot: Q92769).

Immunoaffinity chromatography

55 kD

Small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.