GM-CSF Antibody (1B3E11), mAb, Mouse

USA

This product reacts with human GM-CSF. It has not yet been tested with other species.

Granulocyte-Macrophage-CSF induces myeloid progenitor cells from bone marrow to form colonies containing macrophages and granulocytes in a semisolid media. GM-CSF also acts upon mature macrophages, eosinophils and neutrophils to stimulate various functional activities. GM-CSF is an acidic glycoprotein (23 kD mouse, 18-22 kD human) which binds to high affinity receptors on GM-CSF sensitive cells. Although human and mouse GM-CSF share 54% amino acid sequence homology, their biological actions are species-specific. Other growth factors and CSFs modulate receptor binding or actions of GM-CSF.

GM-CSF full length recombinant protein

Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.