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NMDAR1 Antibody, pAb, Rabbit

NMDAR1 Antibody, pAb, Rabbit

Item no.	A01587-40
Manufacturer	GenScript
Amount	40 ug
Quantity options	100 ug 40 ug
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, FC, other
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A01587-NMDAR1_antibody_pAb_Rabbit,GRIN1 Antibody, ,
Similar products	NMDAR1
Available
Specificity	GenScript NMDAR1 Antibody, detects endogenous levels of mouse NMDAR1. It is predicted to react with human and rat NMDAR1 protein according to sequence homology. Positive Control: Mouse brain
Manufacturer - Isotype	Rabbit IgG
Country of Origin	USA
Storage Conditions	The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity	GenScript NMDAR1 Antibody, detects endogenous levels of mouse NMDAR1. It is predicted to react with human and rat NMDAR1 protein according to sequence homology. Positive Control: Mouse brain
Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Description	N-methyl-D-aspartate receptor (NMDAR) forms a heterodimer of at least one NMDAR1 and one NR2A-D subunit. NMDAR1 subunits and NR2 subunits bind to the co-agonist glycine and the neurotransmitter glutamate, respectively. PKC can phosphorylate NMDAR1 of the receptor at Ser890/Ser896, and PKA can phosphorylate NMDAR1 at Ser897. The phosphorylation of NMDAR1 by PKC decreases its affinity for calmodulin, thus preventing the inhibitory effect of calmodulin on NMDAR. The phosphorylation of NMDAR1 by PKA probably counteracts the inhibitory effect of calcineurin on the receptor. GenScript NMDAR1 Antibody, is developed in rabbit using a KLH-coupled synthetic peptide within residues 900-950 of human NMDAR1 (Swiss Prot: Q05586).
Immunogen	KLH-coupled synthetic peptide within residues 900-950 of human NMDAR1 (Swiss Prot: Q05586)
Purification Method	Immunoaffinity chromatography
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Observed Band Size	120 KD
Predicted Band Size	105 KD

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 40 ug

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Delivery expected until 1/8/2026

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