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MeCP2 antibody, pAb, Rabbit

MeCP2 antibody, pAb, Rabbit

Item no.	A01617-40
Manufacturer	GenScript
Amount	40 ug
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Epigenetics Antibodies Primary Antibodies Glial Cell Markers
Type	Antibody Polyclonal
Applications	WB, other
Specific against	Human (Homo sapiens), other
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A01617-MeCP2_antibody_pAb_Rabbit,RTS antibody, pAb, Rabbit,
Similar products	MeCP2
Available
Specificity	Human. This product has not been tested with other species yet.
Manufacturer - Isotype	Rabbit IgG
Country of Origin	USA
Storage Conditions	The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity	GenScript, MeCP2 Antibody, pAb, Rabbit, detects endogenous levels of human MeCP2. It is predicted to react with rat and mouse MeCP2 according to sequence homology. Positive Control: MCF-7
Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description	Methyl CpG binding protein 2 (MeCP2) is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair and is not influenced by sequences flanking the methyl-CpGs. MeCP2 mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. CDKL5 kinase interacts with MeCP2 and mediates its phosphorylation, which suggests that they belong to the same molecular pathway. MeCP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder. GenScript, MeCP2 Antibody, pAb, Rabbit, is developed in rabbit using a KLH-coupled synthetic peptide within residues 310–360 of human MeCP2 (Swiss Prot: P51608).
Immunogen	KLH-coupled synthetic peptide within residues 310–360 of human MeCP2 (Swiss Prot: P51608)
Purification Method	Immunoaffinity chromatography
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Observed Band Size	33 KD
Predicted Band Size	33 KD

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 40 ug

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Delivery expected until 12/4/2025

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