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PU.1 Antibody, pAb, Rabbit

PU.1 Antibody, pAb, Rabbit

Item no.	A01692-40
Manufacturer	GenScript
Amount	40 ug
Category	Food Safety Drugs Neuroscience Neuroinflammation Antibodies Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, other
Specific against	Human (Homo sapiens), other
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A01692-PU.1_Antibody_pAb_Rabbit,PU.1 Antibody, pAb, Rabbit, Spi1 antibody
Similar products	PU.1
Available
Specificity	Human. Reactivity to other species has not been tested yet.
Country of Origin	USA
Storage Conditions	The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity	GenScript PU.1 Antibody, pAb, Rabbit, detects human PU.1 protein.
Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description	PU.1 known as Spi1 and Sfpi1, is an ETS-domain transcription factor essential for the development of myeloid and B-lymphoid cells. In myeloid cells, PU.1 may regulate transcription of both FMS and CD18/11B proteins that are central to the osteoclast phenotype. The failure to express PU.1 might preclude development of osteoclasts, leading to arrested bone resorption and osteopetrosis. PU.1 expression increases with the induction of osteoclastogenesis by either 1, 25-dihydroxyvitamin D3 or dexamethasone which confirms the association between PU.1 and osteoclast differentiation. GenScript PU.1 Antibody, pAb, Rabbit, is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human PU.1 protein (Swiss Prot: P17947).
Immunogen	KLH-coupled synthetic peptide from C-terminal of human PU.1 (Swiss Prot: P17947)
Purification Method	Immunoaffinity chromatography
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 40 ug

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Delivery expected until 9/25/2025

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